Value across time and context in the maturing human brain Anastasia Christakou University of Reading The decision-making brain is a moving target. The criteria we apply to evaluate the outcomes of our decisions change from moment to moment, as experience is unfolding, and across a longer time-frame, as we mature. How can we study such a dynamical system? In recent and ongoing work, we study the neural mechanisms that evaluate the outcomes of our decisions, and how these evaluative processes guide future behavioural policies. This work highlights the involvement of the ventromedial prefrontal cortex (vmPFC) in the context-sensitive evaluation of decision outcomes across domains (e.g. symbolic or social), and across development. Maturation of networks involving the vmPFC underpin maturational gains in decision-making sophistication, and may underpin age-related differences in decision-making in later life.